Serum Sickness Following Administration of Antivenin (Crotalidae) Polyvalent in 181 Cases of Presumed Rattlesnake Envenomation☆
نویسندگان
چکیده
منابع مشابه
Antivenin-related serum sickness.
Serum sickness is a type III hypersensitivity reaction that occurs due to the deposition of excessive circulating immune complexes in patients treated with foreign proteins or haptens. Serum sickness induced by antivenin for snakebites has been frequently reported in the USA, but not in Taiwan. This difference may be due to the efficacy and dosage of antivenins administered to treat snakebites ...
متن کاملAbstracts from the CAL/ACEP Scientific Assembly, Long Beach, CA 2002
Objective: Pediatric cases comprise approximately 22% of rattlesnake envenomations in the U.S. The recent introduction of Crotaline Fab antivenom and withdrawal from the market of the traditional antivenom preparation has changed the way rattlesnake envenomation is treated. Although in some hospitals Crotaline Fab antivenom may be the only antivenom currently available, there is little data reg...
متن کاملContinuous IV Crotalidae Polyvalent Immune Fab (Ovine) (FabAV) for selected North American rattlesnake bite patients.
BACKGROUND In patients bitten by North American rattlesnakes and treated with Crotalidae Polyvalent Immune Fab (Ovine) (FabAV), late hematologic abnormalities-persistent, recurrent, or late, new onset of hypofibrinogenemia, prolonged PT/INR, prolonged PTT, and/or thrombocytopenia beyond 48 h post-envenomation-are common, difficult to manage, and may result in morbidity and mortality are common,...
متن کاملCrofab Crotalidae Polyvalent Immune Fab (ovine)
-----------------DOSAGE AND ADMINISTRATION---------------For intravenous use only Initiate administration as soon as possible after snake bite in patients who develop signs of envenomation (e.g. local injury, coagulation abnormality or systemic signs of envenomation) Dose: (2.1) o Recommended initial dose is between 4 and 6 vials o Observe patient for up to one hour after the initial dose a...
متن کاملMojave rattlesnake envenomation: prolonged neurotoxicity and rhabdomyolysis.
An 11-year-old girl presented to the emergency department with hypoventilation and shock after being bitten by a Mojave rattlesnake. Intubation was required, and she improved rapidly after fluid resuscitation and antivenom administration. She was extubated four hours after envenomation and did well. The patient subsequently developed increased weakness and cranial nerve paresis and required rei...
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ژورنال
عنوان ژورنال: Wilderness & Environmental Medicine
سال: 2003
ISSN: 1080-6032
DOI: 10.1580/1080-6032(2003)14[220:ssfaoa]2.0.co;2